A10 vs Instinct MI325X
NVIDIA A10 (Ampere, 24 GB) against AMD Instinct MI325X (CDNA 3, 256 GB): memory, compute, power and rental price, compared for LLM inference and training.
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Side-by-Side Specifications
| Spec | A10 | Instinct MI325X |
|---|---|---|
| Architecture | Ampere | CDNA 3 |
| Memory | 24 GB GDDR6 | 256 GB HBM3e |
| Memory bandwidth | 600 GB/s | 6,000 GB/s |
| FP16 tensor compute | 250 TFLOPS | 2,615 TFLOPS |
| INT8 tensor compute | 500 TOPS | 5,230 TOPS |
| Interconnect | PCIe 4.0 · 64 GB/s | Infinity Fabric 3 · 896 GB/s |
| TDP | 150 W | 1000 W |
| Est. on-demand price | ~$1.00/h | ~$8.00/h |
| FP16 TFLOPS per $/h | 250 | 327 |
Highlighted values indicate the stronger spec. Hourly rates are indicative on-demand estimates.
Verdict
Raw performance: The Instinct MI325X leads on FP16 tensor compute (10.5x advantage), which translates directly into higher token throughput for inference and shorter training steps.
Memory: With 256 GB per card, the Instinct MI325X fits larger models on fewer GPUs - fewer cards means less inter-GPU communication and simpler deployments.
Value: At current on-demand rates, the Instinct MI325X delivers more compute per dollar (327 vs 250 FP16 TFLOPS per $/h). If your model fits in its VRAM budget, it is usually the more economical choice.
GPUs Needed for Popular LLMs
Cards required to serve each model at 8-bit quantization (with 20% overhead for activations and KV cache).
| Model | VRAM (8-bit) | A10 | Instinct MI325X |
|---|---|---|---|
| GPT-5.6 Sol | 2682 GB | 112x | 11x |
| GLM 5.3 (743B) | 830 GB | 35x | 4x |
| Claude 4.8 Opus (300B) | 335 GB | 14x | 2x |
| Grok 3 Mini | 212 GB | 9x | 1x |
| Qwen 3.6 Plus (110B) | 123 GB | 6x | 1x |
| Nova Core (34B) | 38 GB | 2x | 1x |
| Phi 4 (14B) | 16 GB | 1x | 1x |
| Mage VL | 5 GB | 1x | 1x |
| LFM 2.5 2.6B | 3 GB | 1x | 1x |
Frequently Asked Questions
Which is better for LLM inference: A10 or Instinct MI325X?
The Instinct MI325X delivers more raw FP16 compute (2,615 TFLOPS) and the Instinct MI325X offers the most memory per card (256 GB). For cost-efficiency, the Instinct MI325X currently gives more FP16 TFLOPS per dollar of on-demand rental (327 vs 250 TFLOPS per $/h).
How much more memory does the Instinct MI325X have?
The A10 has 24 GB of GDDR6 versus 256 GB of HBM3e for the Instinct MI325X - a ratio of 10.67x in favor of the Instinct MI325X. More VRAM per card means fewer GPUs to fit a given model.
Is the A10 or the Instinct MI325X cheaper to rent?
Estimated on-demand rates are ~$1.00/h for the A10 and ~$8.00/h for the Instinct MI325X. Raw hourly price is only part of the story: normalize by throughput (TFLOPS per $/h) and by how many cards you need for your model's VRAM.
How do the A10 and Instinct MI325X compare on power?
The A10 has a TDP of 150W versus 1000W for the Instinct MI325X. FP16 compute per watt: 1.7 vs 2.6 TFLOPS/W.
Deploy on a GPU cloud
Rent the A10 or Instinct MI325X by the hour instead of buying hardware.
